Screening of oral premalignant lesions in smokers using toluidine blue

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The adjunctive role of toluidine blue in detection of oral premalignant and malignant lesions.

PURPOSE OF REVIEW To review the literature on toluidine blue (TBlue) and to discuss the utility of TBlue in assessing and in clinical management of patients with oral mucosal lesions. The literature search was conducted using key word search including oral cancer, oral premalignant lesions, and TBlue and by selecting references from the articles reviewed. RECENT FINDINGS The findings of this ...

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Diagnostic efficiency of toluidine blue with Lugol's iodine in oral premalignant and malignant lesions.

BACKGROUND AND OBJECTIVES In vivo stains are prompt resources, which have emerged, in the recent years, to aid as clinical diagnostic tools in detecting early premalignant and malignant lesions. The aim of the study was to determine the diagnostic efficiency of toluidine blue with Lugol's iodine in oral premalignancies and malignancies and to evaluate the reliability of in vivo staining with to...

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Toluidine blue staining identifies high-risk primary oral premalignant lesions with poor outcome.

There is a pressing need for the development of visual aids that will facilitate the detection of oral premalignant lesions (OPLs) with a high-risk of progression. Preliminary data suggest that toluidine blue stain may be preferentially retained by OPLs with high-risk molecular clones. In this study, we monitored OPLs from 100 patients without any history of oral cancer for an average of 44 mon...

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Histopathologic evaluation of mast cells in reticular and erosive oral lichen planus using toluidine blue staining

Introduction: Oral Lichen Planus (OLP) is one of the most common mucocutaneous lesion, and its etiologic factors have not been elucidated yet. OLP has two different clinical forms including reticular and erosive. Mast cells function in non-specific immunology is an etiologic factor involved in the formation of lichen planus. This study aimed at determining the pattern of mast cells presence in ...

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The use of toluidine blue in the detection of pre-malignant and malignant oral lesions.

INTRODUCTION The purpose of this study was to evaluate the efficacy of the toluidine blue (TB) test as a diagnostic tool in the detection of malignant and dysplastic lesions of the oral cavity. This study was carried out because of a lack of consensus among different authors on the utility of TB, as well as to determine useful adjuncts to detect oral pre-cancer and cancer. MATERIALS AND METHO...

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ژورنال

عنوان ژورنال: Dental Journal (Majalah Kedokteran Gigi)

سال: 2009

ISSN: 2442-9740,1978-3728

DOI: 10.20473/j.djmkg.v42.i2.p90-93